The FTSE 100 (^FTSE) and European stocks were lower as traders look ahead to US inflation figures due out later on Wednesday, which could cement the path for interest rate cuts.
Analysts are expecting the annual rate of the consumer prices index to rise to 2.7% from 2.6%, while the core measure, which strips out volatile items like food and energy, is forecast to remain at 3.3%.
The data will be followed by a further reading on Thursday at the wholesale level.
Richard Hunter, head of markets at Interactive Investor, said: “Barring any shocks, the likelihood of an interest rate cut is high next week, although expectations have been dialled back on the pace of reductions next year.
“The twin drivers of a surprisingly robust economy which has shown few signs of heading towards the previously feared recession, alongside some caution that the President elect is likely to introduce some measures which are inflationary, could well keep a lid on the monetary easing path.”
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London’s benchmark index was 0.35% down in early trade, with mining stocks falling again in a sign of investor uncertainty.
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Germany’s DAX (^GDAXI) dipped 0.1% and the CAC (^FCHI) in Paris headed 0.2% into the green.
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The pan-European STOXX 600 (^STOXX) lost around 0.25%.
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Wall Street is set for a mostly positive start as S&P 500 futures (ES=F) and Nasdaq futures (NQ=F) were in the green, while Dow futures (YM=F) slipped.
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The pound was 0.1% down against the US dollar (GBPUSD=X) at 1.2755.
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