The campaign rallies in Pennsylvania and Wisconsin, two key swing states, will be followed by an interview broadcast on ABC News on Sunday.
Aides reportedly hope that they will help Democrats to set aside concerns about his age and mental agility.
However, the calls for Mr Biden to reconsider his campaign continued yesterday, amid reports that some House Democrats are organising a letter calling for him to stand down.
Reed Hastings, a major Democratic Party donor and a co-founder of the streaming platform Netflix, on Wednesday joined those calling on Mr Biden to stand down.
“Biden needs to step aside to allow a vigorous Democratic leader to beat Trump and keep us safe and prosperous,” he was quoted as saying in an email to The New York Times.
Two Democrat congressmen, Lloyd Doggett and Raul Grijalva, have called on Mr Biden to make the decision to withdraw, while two other sitting Democrats have said they think he will lose the election to Trump.
“If [Mr Biden] is the candidate, I’m going to support him, but I think that this is an opportunity to look elsewhere,” said Mr Grijalva, a Democrat representative from Arizona.
“What he needs to do is shoulder the responsibility for keeping that seat — and part of that responsibility is to get out of this race.”