The 61 year-old is from the village of al-Nabi Shayth, in the Baalbek district of Lebanon, also the birthplace of Hezbollah co-founder Abbas al-Musawi.
Shukr serves on the Jihad Council, Hezbollah’s highest military body, and has allegedly been involved in assisting Hezbollah fighters and pro-Assad forces in the Syrian civil war.
The strike hit near Hezbollah’s Shura Council, the group’s central decision-making authority.
Hezbollah-affiliated media Al Mayadeen reported that a four-floor residential building had “completely collapsed” and that the Bahman Hospital was partially damaged too.
The attack came after Mr Netanyahu vowed a “severe response” to the Golan Heights attack.
Yoav Gallant, Israel’s defence minister, said Hezbollah “crossed a red line” shortly after the attack was confirmed by the IDF.
Israel warned the US ahead of the strike, CNN reported citing a source familiar with the matter.
Shortly after the attack, US deputy state department spokesman Vedant Patel said that Washington was still “continuing to work toward a diplomatic resolution that would allow Israeli and Lebanese civilians to return to their homes and live in peace and security.
“We certainly want to avoid any kind of escalation.”
The Iranian Embassy, in Lebanon, said it condemned in the “strongest terms the cowardly and sinful Israeli aggression that targeted the southern suburb of Beirut, which claimed the lives of a number of martyrs and wounded.”